Human induced pluripotent stem cell-derived closed-loop cardiac tissue for drug assessment

Human induced pluripotent stem cell-derived closed-loop cardiac tissue for drug assessment

Summary: Human iPSC-derived cardiomyocytes (hiPSC-CMs) exhibit functional immaturity, potentially impacting their suitability for assessing drug proarrhythmic potential. We previously devised a traveling wave (TW) system to promote maturation in 3D cardiac tissue. To align with current drug assessme...

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Bibliographic Details
Main Authors: Junjun Li, Ying Hua, Yuting Liu, Xiang Qu, Jingbo Zhang, Masako Ishida, Noriko Yoshida, Akiko Tabata, Hayato Miyoshi, Mikio Shiba, Shuichiro Higo, Nagako Sougawa, Maki Takeda, Takuji Kawamura, Ryohei Matsuura, Daisuke Okuzaki, Toshihiko Toyofuku, Yoshiki Sawa, Li Liu, Shigeru Miyagawa
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:iScience
Subjects:
Bioengineering
Biotechnology
Cardiovascular medicine
Stem cells research
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422400213X

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http://www.sciencedirect.com/science/article/pii/S258900422400213X

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