Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer

Preventing ovariectomy-induced weight gain decreases tumor burden in rodent models of obesity and postmenopausal breast cancer

Abstract Background Obesity and adult weight gain are linked to increased breast cancer risk and poorer clinical outcomes in postmenopausal women, particularly for hormone-dependent tumors. Menopause is a time when significant weight gain occurs in many women, and clinical and preclinical studies ha...

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Bibliographic Details
Main Authors: Elizabeth A. Wellberg, Karen A. Corleto, L. Allyson Checkley, Sonali Jindal, Ginger Johnson, Janine A. Higgins, Sarina Obeid, Steven M. Anderson, Ann D. Thor, Pepper J. Schedin, Paul S. MacLean, Erin D. Giles
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Breast Cancer Research
Subjects:
Diet
Obesity
Animal models
Cancer interception
Inflammation
Cytokines
Online Access:https://doi.org/10.1186/s13058-022-01535-x

Internet

https://doi.org/10.1186/s13058-022-01535-x

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