Effect of N-glycosylation on horseradish peroxidase structural and dynamical properties

Effect of N-glycosylation on horseradish peroxidase structural and dynamical properties

The effect of different branching types of glycosylation on the structure and dynamics of the horseradish peroxidase (HRP) and an engineered split horseradish peroxidase (sHRP) was studied using all-atom molecular dynamics (MD) simulations. Although tertiary structures of both proteins are stable in...

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Bibliographic Details
Main Authors: Sanja Škulj, Antun Barišić, Natalie Mutter, Oliver Spadiut, Ivan Barišić, Branimir Bertoša
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
N-glycosylation
Horseradish peroxidase – HRP
Glycoprotein
Mutations
Molecular dynamics simulations
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037022002227

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http://www.sciencedirect.com/science/article/pii/S2001037022002227

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