High resolution structures define divergent and convergent mechanisms of archaeal proteasome activation
Abstract Considering the link between neurodegenerative diseases and impaired proteasome function, and the neuro-protective impact of enhanced proteasome activity in animal models, it’s crucial to understand proteasome activation mechanisms. A hydrophobic-tyrosine-any residue (HbYX) motif on the C-t...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-07-01
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Series: | Communications Biology |
Online Access: | https://doi.org/10.1038/s42003-023-05123-3 |