High resolution structures define divergent and convergent mechanisms of archaeal proteasome activation

Abstract Considering the link between neurodegenerative diseases and impaired proteasome function, and the neuro-protective impact of enhanced proteasome activity in animal models, it’s crucial to understand proteasome activation mechanisms. A hydrophobic-tyrosine-any residue (HbYX) motif on the C-t...

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Bibliographic Details
Main Authors: Janelle J. Y. Chuah, Matthew S. Rexroad, David M. Smith
Format: Article
Language:English
Published: Nature Portfolio 2023-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-023-05123-3

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