Female resistance to pneumonia identifies lung macrophage nitric oxide synthase-3 as a therapeutic target
To identify new approaches to enhance innate immunity to bacterial pneumonia, we investigated the natural experiment of gender differences in resistance to infections. Female and estrogen-treated male mice show greater resistance to pneumococcal pneumonia, seen as greater bacterial clearance, dimini...
Main Authors: | , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-10-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/03711 |