Insights into pancreatic β cell energy metabolism using rodent β cell models [version 3; peer review: 2 approved, 1 not approved]

Insights into pancreatic β cell energy metabolism using rodent β cell models [version 3; peer review: 2 approved, 1 not approved]

Background: Mitochondrial diabetes is primarily caused by β-cell failure, a cell type whose unique properties are important in pathogenesis. Methods: By reducing glucose, we induced energetic stress in two rodent β-cell models to assess effects on cellular function. Results: Culturing rat insulin-se...

Full description

Bibliographic Details
Main Authors: Karl J Morten, Michelle Potter, Luned Badder, Pamela Sivathondan, Rebecca Dragovic, Abigale Neumann, James Gavin, Roshan Shrestha, Svetlana Reilly, Kanchan Phadwal, Tiffany A. Lodge, Angela Borzychowski, Sharon Cookson, Corey Mitchell, Alireza Morovat, Anna Katharina Simon, Johanna Uusimaa, James Hynes, Joanna Poulton
Format: Article
Language:English
Published: Wellcome 2019-09-01
Series:Wellcome Open Research
Subjects:
pancreas
Online Access:https://wellcomeopenresearch.org/articles/2-14/v3

Internet

https://wellcomeopenresearch.org/articles/2-14/v3

Similar Items