Focal adhesion kinase inhibitor PF573228 and death receptor 5 agonist lexatumumab synergistically induce apoptosis in pancreatic carcinoma
Pancreatic cancer has one of the lowest survival rates of all cancers. The mechanism underlying chemo-resistance of pancreatic cancer is not well understood. Our previous article reported that small molecule YM155 induced apoptosis in pancreatic cancer cells via activation of death receptor 5. In th...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
IOS Press
2017-04-01
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Series: | Tumor Biology |
Online Access: | https://doi.org/10.1177/1010428317699120 |