Regulatory crosstalk by protein kinases on CFTR trafficking and activity

Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) is a member of the ATP binding cassette (ABC) transporter superfamily that functions as a cAMP-activated chloride ion channel in fluid-transporting epithelia. There is abundant evidence that CFTR activity (i.e. channel opening and closing) i...

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Библиографические подробности
Главные авторы: Carlos Miguel eFarinha, Agnieszka eSwiatecka-Urban, David L Brautigan, Peter eJordan
Формат: Статья
Язык:English
Опубликовано: Frontiers Media S.A. 2016-01-01
Серии:Frontiers in Chemistry
Предметы:
Online-ссылка:http://journal.frontiersin.org/Journal/10.3389/fchem.2016.00001/full