Comparative analysis of antibiotic exposure association with clinical outcomes of chemotherapy versus immunotherapy across three tumour types

Background In solid tumours, antibiotic use during immune checkpoint inhibitor (ICI) treatment is associated with shorter survival. Following allogeneic haematopoietic cell transplantation (allo-HCT), antibiotic-induced gut microbiome alterations are associated with risk of relapse and mortality. Th...

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Bibliographic Details
Main Authors: Todd Defor, Daniel Weisdorf, Ryan Shanley, Amit A Kulkarni, Maryam Ebadi, Shijia Zhang, Mohamad A Meybodi, Alaa M Ali, Charles Ryan, Sumithira Vasu, Armin Rashidi, Manish Ramesh Patel
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:ESMO Open
Online Access:https://esmoopen.bmj.com/content/5/5/e000803.full