Tracing G-Protein-Mediated Contraction and Relaxation in Vascular Smooth Muscle Cell Spheroids

Tracing G-Protein-Mediated Contraction and Relaxation in Vascular Smooth Muscle Cell Spheroids

Analyses of G-protein-mediated contraction and relaxation of vascular smooth muscle cells (VSMCs) are usually hampered by a rigid growth surface and culture conditions promoting cell proliferation and a less contractile phenotype. Our studies indicated that mouse aortic VSMCs cultured in three-dimen...

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Bibliographic Details
Main Authors: Jaspal Garg, Alexandra Sporkova, Markus Hecker, Thomas Korff
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
G-protein signaling
RGS
VSMC phenotype
MAPK
contraction
relaxation
Online Access:https://www.mdpi.com/2073-4409/12/1/128

Internet

https://www.mdpi.com/2073-4409/12/1/128

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