Systematic identification of cancer-specific MHC-binding peptides with RAVEN

Systematic identification of cancer-specific MHC-binding peptides with RAVEN

Immunotherapy can revolutionize anti-cancer therapy if specific targets are available. Immunogenic peptides encoded by cancer-specific genes (CSGs) may enable targeted immunotherapy, even of oligo-mutated cancers, which lack neo-antigens generated by protein-coding missense mutations. Here, we descr...

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Bibliographic Details
Main Authors: Michaela C. Baldauf, Julia S. Gerke, Andreas Kirschner, Franziska Blaeschke, Manuel Effenberger, Kilian Schober, Rebeca Alba Rubio, Takayuki Kanaseki, Merve M. Kiran, Marlene Dallmayer, Julian Musa, Nurset Akpolat, Ayse N. Akatli, Fernando C. Rosman, Özlem Özen, Shintaro Sugita, Tadashi Hasegawa, Haruhiko Sugimura, Daniel Baumhoer, Maximilian M. L. Knott, Giuseppina Sannino, Aruna Marchetto, Jing Li, Dirk H. Busch, Tobias Feuchtinger, Shunya Ohmura, Martin F. Orth, Uwe Thiel, Thomas Kirchner, Thomas G. P. Grünewald
Format: Article
Language:English
Published: Taylor & Francis Group 2018-09-01
Series:OncoImmunology
Subjects:
immunotherapy
bioinformatics
microarray
cancer-specific genes
Online Access:http://dx.doi.org/10.1080/2162402X.2018.1481558

Internet

http://dx.doi.org/10.1080/2162402X.2018.1481558

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