A microglial activation cascade across cortical regions underlies secondary mechanical hypersensitivity to amputation

A microglial activation cascade across cortical regions underlies secondary mechanical hypersensitivity to amputation

Summary: Neural mechanisms underlying amputation-related secondary pain are unclear. Using in vivo two-photon imaging, three-dimensional reconstruction, and fiber photometry recording, we show that a microglial activation cascade from the primary somatosensory cortex of forelimb (S1FL) to the primar...

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Bibliographic Details
Main Authors: Hong-Rui Wei, Lan Tang, Xin-Lu Yang, Chang-Mao Chen, Le-Xian Li, Yu Mao, Di Wang, Fang Kang, Sen Qun, Zhi Zhang, Peng Cao, Yan Jin
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Cell Reports
Subjects:
CP: Neuroscience
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724001323

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http://www.sciencedirect.com/science/article/pii/S2211124724001323

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