METTL3 promotes chemoresistance in small cell lung cancer by inducing mitophagy

Abstract Background Small cell lung cancer (SCLC) is the most aggressive subtype of lung cancer. Although most patients are initially sensitive to first-line combination chemotherapy with cisplatin and etoposide, chemotherapy drug resistance easily develops and quickly leads to tumour progression. T...

Full description

Bibliographic Details
Main Authors: Yueqin Sun, Weitao Shen, Shulu Hu, Qiong Lyu, Qiongyao Wang, Ting Wei, Weiliang Zhu, Jian Zhang
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Online Access:https://doi.org/10.1186/s13046-023-02638-9