Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ
YAP (yes-associated protein) and TAZ are oncogenic transcriptional co-activators downstream of the Hippo tumor-suppressor pathway. However, whether YAP and/or TAZ (YAP/TAZ) engage in transcriptional co-repression remains relatively unexplored. Here, we directly demonstrated that YAP/TAZ represses nu...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2015-04-01
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Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124715002685 |