Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ

YAP (yes-associated protein) and TAZ are oncogenic transcriptional co-activators downstream of the Hippo tumor-suppressor pathway. However, whether YAP and/or TAZ (YAP/TAZ) engage in transcriptional co-repression remains relatively unexplored. Here, we directly demonstrated that YAP/TAZ represses nu...

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Bibliographic Details
Main Authors: Minchul Kim, Taekhoon Kim, Randy L. Johnson, Dae-Sik Lim
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715002685