Regulation of the expression of chaperone gp96 in macrophages and dendritic cells.

Regulation of the expression of chaperone gp96 in macrophages and dendritic cells.

The chaperone function of the ER-residing heat shock protein gp96 plays an important role in protein physiology and has additionally important immunological functions due to its peptide-binding capacity. Low amounts of gp96 stimulate immunity; high quantities induce tolerance by mechanisms not fully...

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Bibliographic Details
Main Authors: Lutz Wolfram, Anne Fischbeck, Isabelle Frey-Wagner, Kacper A Wojtal, Silvia Lang, Michael Fried, Stephan R Vavricka, Martin Hausmann, Gerhard Rogler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3797789?pdf=render

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http://europepmc.org/articles/PMC3797789?pdf=render

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