Isolation of rat hepatocytes for pharmacological studies on metabotropic glutamate receptor (mGluR) subtype 5: a comparison between collagenase I versus collagenase IV

Isolated hepatocytes can be obtained from the liver by collagenase infusion, a procedure that could affect cell isolation as well as the integrity of membrane receptors. In this respect we compared metabotropic glutamate subtype 5 receptor (mGluR5) protein expression and activity in rat hepatocytes...

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Bibliographic Details
Main Authors: Clarissa Berardo, Andrea Ferrigno, Veronica Siciliano, Plinio Richelmi, Mariapia Vairetti, Laura Giuseppina Di Pasqua
Format: Article
Language:English
Published: PAGEPress Publications 2020-03-01
Series:European Journal of Histochemistry
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Online Access:https://www.ejh.it/index.php/ejh/article/view/3123