Secretory SERPINE1 Expression Is Increased by Antiplatelet Therapy, Inducing MMP1 Expression and Increasing Colon Cancer Metastasis

Contrary to many reports that antiplatelet agents inhibit cancer growth and metastasis, new solid tumors have been reported in patients receiving long-term antiplatelet therapy. We investigated the effects of these agents directly on cancer cells in the absence of platelets to mimic the effects of l...

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Bibliographic Details
Main Authors: Won-Tae Kim, Jeong-Yeon Mun, Seung-Woo Baek, Min-Hye Kim, Gi-Eun Yang, Mi-So Jeong, Sun Young Choi, Jin-Yeong Han, Moo Hyun Kim, Sun-Hee Leem
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/17/9596