Metabolism of Reactive Oxygen Species in Osteosarcoma and Potential Treatment Applications

Metabolism of Reactive Oxygen Species in Osteosarcoma and Potential Treatment Applications

Background: The present study was designed to explore the underlying role of hypoxia-inducible factor 1α (HIF-1α) in reactive oxygen species (ROS) formation and apoptosis in osteosarcoma (OS) cells induced by hypoxia. Methods: In OS cells, ROS accumulated and apoptosis increased wi...

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Bibliographic Details
Main Authors: Wei Sun, Bing Wang, Xing-Long Qu, Bi-Qiang Zheng, Wen-Ding Huang, Zheng-Wang Sun, Chun-Meng Wang, Yong Chen
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Cells
Subjects:
osteosarcoma
ros
hif-1α
foxo1
microarray
Online Access:https://www.mdpi.com/2073-4409/9/1/87

Internet

https://www.mdpi.com/2073-4409/9/1/87

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