Sevoflurane postconditioning improves spatial learning and memory ability involving mitochondrial permeability transition pore in hemorrhagic shock and resuscitation rats

Abstract Background Hemorrhagic shock induces the cognitive deficiency. Sevoflurane postconditioning has been documented to provide neuroprotection against ischemic–reperfusion injury by suppressing apoptosis. Mitochondrial permeability transition pore (mPTP) plays an important role in apoptosis, bu...

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Bibliographic Details
Main Authors: Li Zhang, Li Huang, Jingxian Wang, Muchun Zhang, Ye Zhang, Xianwen Hu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Brain and Behavior
Subjects:
Online Access:https://doi.org/10.1002/brb3.1501