Lactobacillus acidophilus and propionate attenuate Sjögren’s syndrome by modulating the STIM1-STING signaling pathway

Lactobacillus acidophilus and propionate attenuate Sjögren’s syndrome by modulating the STIM1-STING signaling pathway

Abstract Background Sjögren’s syndrome (SS) is an autoimmune disease characterized by inflammation of the exocrine gland. An imbalance of gut microbiota has been linked to SS. However, the molecular mechanism is unclear. We investigated the effects of Lactobacillus acidophilus (L. acidophilus) and p...

Full description

Bibliographic Details
Main Authors: Jin Seok Woo, Sun-Hee Hwang, SeungCheon Yang, Kun Hee Lee, Yeon Su Lee, Jeong Won Choi, Jin-Sil Park, JooYeon Jhun, Sung-Hwan Park, Mi-La Cho
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Cell Communication and Signaling
Subjects:
Sjögren’s syndrome
Lactobacillus acidophilus
Propionate
Stromal interaction moleculae 1 (STIM1)
Stimulation of interferon genes (STING)
Online Access:https://doi.org/10.1186/s12964-023-01141-0

Internet

https://doi.org/10.1186/s12964-023-01141-0

Similar Items