Skp2 modulates proliferation, senescence and tumorigenesis of glioma

Skp2 modulates proliferation, senescence and tumorigenesis of glioma

Abstract Background Gliomas represent the largest class of primary central nervous system neoplasms, many subtypes of which exhibit poor prognoses. Surgery followed by radiotherapy and chemotherapy has been used as a standard strategy but yielded unsatisfactory improvements in patient survival outco...

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Bibliographic Details
Main Authors: Juan Wu, Hong-kai Su, Zhi-hui Yu, Shao-yan Xi, Cheng-cheng Guo, Zhe-yu Hu, Yue Qu, Hai-ping Cai, Yi-ying Zhao, Hua-fu Zhao, Fu-rong Chen, Yu-fan Huang, Shing-shun Tony To, Bing-hong Feng, Ke Sai, Zhong-ping Chen, Jing Wang
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cancer Cell International
Subjects:
Glioma
S-phase kinase-associated protein 2 (Skp2)
Glioma stem-like cells
Lovastatin
SZL-P1-41
Online Access:http://link.springer.com/article/10.1186/s12935-020-1144-z

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http://link.springer.com/article/10.1186/s12935-020-1144-z

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