Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP
How archaeal viruses perturb host transcription machinery is poorly understood. Here, the authors provide evidence that the archaeo-viral transcription factor ORF145/RIP targets host RNA polymerase, repressing its activity.
Main Authors: | , , , , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2016-11-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/ncomms13595 |