Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP
How archaeal viruses perturb host transcription machinery is poorly understood. Here, the authors provide evidence that the archaeo-viral transcription factor ORF145/RIP targets host RNA polymerase, repressing its activity.
Bibliographic Details
Main Authors: |
Carol Sheppard,
Fabian Blombach,
Adam Belsom,
Sarah Schulz,
Tina Daviter,
Katherine Smollett,
Emilie Mahieu,
Susanne Erdmann,
Philip Tinnefeld,
Roger Garrett,
Dina Grohmann,
Juri Rappsilber,
Finn Werner |
Format: | Article
|
Language: | English |
Published: |
Nature Portfolio
2016-11-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/ncomms13595
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