The protective role of symmetric stem cell division on the accumulation of heritable damage.
Stem cell divisions are either asymmetric-in which one daughter cell remains a stem cell and one does not-or symmetric, in which both daughter cells adopt the same fate, either stem or non-stem. Recent studies show that in many tissues operating under homeostatic conditions stem cell division patter...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-08-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4133021?pdf=render |