Apolipoprotein E ε4 accelerates the longitudinal cerebral atrophy in open access series of imaging studies-3 elders without dementia at enrollment

IntroductionEarly studies have reported that APOE is strongly associated with brain atrophy and cognitive decline among healthy elders and Alzheimer’s disease (AD). However, previous research has not directly outlined the modulation of APOE on the trajectory of cerebral atrophy with aging during the...

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Bibliographic Details
Main Authors: Yuda Huang, Yongzhi Shan, Wen Qin, Guoguang Zhao
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Aging Neuroscience
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2023.1158579/full