Physicochemical properties of acedoben and its trifluoroacetamido derivative

Acedoben (4-acetamidobenzoic acid, AcPABA) is a component of the antiviral drug inosine pranobex. The introduction of fluorine has been proven to change the physicochemical properties of molecules. For example, the trifluoromethyl group generally improves the lipophilicity of molecules, which is an...

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Bibliographic Details
Main Authors: Joshua A. Boldon, Thomas A. Shell
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Results in Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623003144