The relationship between sphingosine-1-phosphate receptor 2 and epidermal growth factor in migration and invasion of oral squamous cell carcinoma

Abstract Sphingosine-1-phosphate (S1P) is a lipid mediator and its binding to the S1P receptor 2 (S1PR2) is reported to regulate cytoskeletal organization. Epidermal growth factor (EGF) has been shown to induce migration and invasion in tumour cells. Since binding of S1P to S1PR2 and EGF to the EGF...

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Bibliographic Details
Main Authors: Adjabhak Wongviriya, Richard M. Shelton, Paul R. Cooper, Michael R. Milward, Gabriel Landini
Format: Article
Language:English
Published: BMC 2023-04-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-023-02906-w