Proliferation-Independent Initiation of Biliary Cysts in Polycystic Liver Diseases.

Biliary cysts in adult patients affected by polycystic liver disease are lined by cholangiocytes that proliferate, suggesting that initiation of cyst formation depends on proliferation. Here, we challenge this view by analyzing cyst-lining cell proliferation and differentiation in Cpk mouse embryos...

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Bibliographic Details
Main Authors: Jean-Bernard Beaudry, Sabine Cordi, Céline Demarez, Sébastien Lepreux, Christophe E Pierreux, Frédéric P Lemaigre
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4488361?pdf=render