The Effects of a Biomimetic Hybrid Meso- and Nano-Scale Surface Topography on Blood and Protein Recruitment in a Computational Fluid Dynamics Implant Model

The mechanisms underlying bone-implant integration, or osseointegration, are still incompletely understood, in particular how blood and proteins are recruited to implant surfaces. The objective of this study was to visualize and quantify the flow of blood and the model protein fibrinogen using a com...

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Bibliographic Details
Main Authors: Hiroaki Kitajima, Makoto Hirota, Kohei Osawa, Toshinori Iwai, Kenji Mitsudo, Juri Saruta, Takahiro Ogawa
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Biomimetics
Subjects:
Online Access:https://www.mdpi.com/2313-7673/8/4/376