Prothrombotic fibrin clot properties associated with NETs formation characterize acute pulmonary embolism patients with higher mortality risk

Abstract Venous thromboembolism is associated with formation of denser fibrin clots resistant to lysis. We investigated whether prothrombotic plasma clot properties are associated with the severity of acute pulmonary embolism (PE). We enrolled 126 normotensive acute PE patients (aged 58 ± 14 years)...

Full description

Bibliographic Details
Main Authors: Michał Ząbczyk, Joanna Natorska, Agnieszka Janion-Sadowska, Agnieszka Metzgier-Gumiela, Mateusz Polak, Krzysztof Plens, Marianna Janion, Grzegorz Skonieczny, Katarzyna Mizia-Stec, Anetta Undas
Format: Article
Language:English
Published: Nature Portfolio 2020-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-68375-7