Silica Nanoparticles Promote Apoptosis in Ovarian Granulosa Cells via Autophagy Dysfunction

Silica Nanoparticles Promote Apoptosis in Ovarian Granulosa Cells via Autophagy Dysfunction

Although silica nanoparticles (SNPs) are generally thought to be biocompatible and safe, the adverse effects of SNPs were also reported in previous studies. SNPs cause follicular atresia via the induction of ovarian granulosa cell apoptosis. However, the mechanisms for this phenomenon are not well u...

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Bibliographic Details
Main Authors: Zhen Zheng, Wenlong Zuo, Rongrong Ye, Jason William Grunberger, Nitish Khurana, Xianyu Xu, Hamidreza Ghandehari, Fenglei Chen
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:International Journal of Molecular Sciences
Subjects:
autophagy dysfunction
apoptosis
pvarian granulosa cells
lysosomal impairment
silica nanoparticles
Online Access:https://www.mdpi.com/1422-0067/24/6/5189

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https://www.mdpi.com/1422-0067/24/6/5189

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