Serum markers of hepatocyte death and apoptosis are non invasive biomarkers of severe fibrosis in patients with alcoholic liver disease.

Serum markers of hepatocyte death and apoptosis are non invasive biomarkers of severe fibrosis in patients with alcoholic liver disease.

BACKGROUND: Quantification of hepatocyte death is useful to evaluate the progression of alcoholic liver diseases. Our aims were to quantify and correlate the circulating levels of Cytokeratin 18 (CK18) and its caspases-generated fragment to disease severity in heavy alcoholics. METHODOLOGY/PRINCIPAL...

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Main Authors: Vanessa Jeannette Lavallard, Stéphanie Bonnafous, Stéphanie Patouraux, Marie-Christine Saint-Paul, Déborah Rousseau, Rodolphe Anty, Yannick Le Marchand-Brustel, Albert Tran, Philippe Gual
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3060823?pdf=render

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http://europepmc.org/articles/PMC3060823?pdf=render

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