miR-223-3p carried by cancer-associated fibroblast microvesicles targets SORBS1 to modulate the progression of gastric cancer

Abstract Background Cancer-associated fibroblasts (CAFs) aggravate gastric cancer (GC) development. Methods Combined with bioinformatics analysis and literature review, miR-223-3p had high expression in microvesicles (MVs) derived from GC CAFs, and it could modulate SORBS1. miR-223-3p and SORBS1 mRN...

Full description

Bibliographic Details
Main Authors: Xiaoli Jin, Xi Qiu, Yi Huang, Hang Zhang, Kaibo Chen
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Cancer Cell International
Subjects:
Online Access:https://doi.org/10.1186/s12935-022-02513-1