miR-223-3p carried by cancer-associated fibroblast microvesicles targets SORBS1 to modulate the progression of gastric cancer
Abstract Background Cancer-associated fibroblasts (CAFs) aggravate gastric cancer (GC) development. Methods Combined with bioinformatics analysis and literature review, miR-223-3p had high expression in microvesicles (MVs) derived from GC CAFs, and it could modulate SORBS1. miR-223-3p and SORBS1 mRN...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-02-01
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Series: | Cancer Cell International |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12935-022-02513-1 |