Long-Term Anxiety-like Behavior and Microbiota Changes Induced in Mice by Sublethal Doses of Acute Sarin Surrogate Exposure

Long-Term Anxiety-like Behavior and Microbiota Changes Induced in Mice by Sublethal Doses of Acute Sarin Surrogate Exposure

Anxiety disorder is one of the most reported complications following organophosphorus (OP) nerve agent (NA) exposure. The goal of this study was to characterize the long-term behavioral impact of a single low dose exposure to 4-nitrophenyl isopropyl methylphosphonate (NIMP), a sarin surrogate. We ch...

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Bibliographic Details
Main Authors: Sabine François, Stanislas Mondot, Quentin Gerard, Rosalie Bel, Julie Knoertzer, Asma Berriche, Sophie Cavallero, Rachid Baati, Cyrille Orset, Gregory Dal Bo, Karine Thibault
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Biomedicines
Subjects:
4-nitrophenyl isopropyl methylphosphonate
mood disorder
anxiety
sarin surrogate
sublethal exposure
dysbiosis
Online Access:https://www.mdpi.com/2227-9059/10/5/1167

Internet

https://www.mdpi.com/2227-9059/10/5/1167

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