Yeast silent mating type loci form heterochromatic clusters through silencer protein-dependent long-range interactions.

The organization of eukaryotic genomes is characterized by the presence of distinct euchromatic and heterochromatic sub-nuclear compartments. In Saccharomyces cerevisiae heterochromatic loci, including telomeres and silent mating type loci, form clusters at the nuclear periphery. We have employed li...

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Bibliographic Details
Main Authors: Adriana Miele, Kerstin Bystricky, Job Dekker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-05-01
Series:PLoS Genetics
Online Access:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1000478&type=printable