Functional epitopes on hepatitis E virions and recombinant capsids are highly conformation-dependent

Functional epitopes on hepatitis E virions and recombinant capsids are highly conformation-dependent

Hepatitis E virus (HEV) is responsible for epidemic and sporadic acute hepatitis cases, especially in developing countries. Hepatitis E has become a vaccine-preventable disease in recent years with the development of a licensed vaccine. Most functional and neutralizing monoclonal antibodies (mAbs) a...

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Bibliographic Details
Main Authors:	Bin He, Zhigang Zhang, Xinyuan Zhang, Zimin Tang, Chang Liu, Zizheng Zheng, Shaowei Li, Jun Zhang, Ningshao Xia, Qinjian Zhao
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2020-07-01
Series:	Human Vaccines & Immunotherapeutics
Subjects:	conformational epitope functional assessment hepatitis e virus hev p239 vaccine particulate antigen neutralizing antibody serological assay
Online Access:	http://dx.doi.org/10.1080/21645515.2019.1703454

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