Combined analysis of PTEN, HER2, and hormone receptors status: remodeling breast cancer risk profiling

Combined analysis of PTEN, HER2, and hormone receptors status: remodeling breast cancer risk profiling

Abstract Background Phosphatase and tensin homolog (PTEN) loss is associated with tumorigenesis, tumor progression, and therapy resistance in breast cancer. However, the clinical value of PTEN as a biomarker in these patients is controversial. We sought to determine whether the benefit of traditiona...

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Bibliographic Details
Main Authors: Elham Sajjadi, Konstantinos Venetis, Roberto Piciotti, Donatella Gambini, Concetta Blundo, Letterio Runza, Stefano Ferrero, Elena Guerini-Rocco, Nicola Fusco
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Cancer
Subjects:
PTEN
Hormone receptors
Estrogen receptor
Progesterone receptor
HER2
Breast cancer
Online Access:https://doi.org/10.1186/s12885-021-08889-z

Internet

https://doi.org/10.1186/s12885-021-08889-z

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