HSPA12A controls cerebral lactate homeostasis to maintain hippocampal neurogenesis and mood stabilization

Abstract Mood instability, a subjective emotional state defined as rapid mood oscillations of up and down, is a symptom that occurs in several psychiatric disorders, particularly major depressive disorder and bipolar disorder. Heat shock protein A12A (HSPA12A) shows decreased expression in the brain...

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Bibliographic Details
Main Authors: Jialing Wang, Ting Lu, Yali Gui, Xiaojin Zhang, Xiaofei Cao, Yuehua Li, Chuanfu Li, Li Liu, Zhengnian Ding
Format: Article
Language:English
Published: Nature Publishing Group 2023-08-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-023-02573-5