HSPA12A controls cerebral lactate homeostasis to maintain hippocampal neurogenesis and mood stabilization
Abstract Mood instability, a subjective emotional state defined as rapid mood oscillations of up and down, is a symptom that occurs in several psychiatric disorders, particularly major depressive disorder and bipolar disorder. Heat shock protein A12A (HSPA12A) shows decreased expression in the brain...
Main Authors: | Jialing Wang, Ting Lu, Yali Gui, Xiaojin Zhang, Xiaofei Cao, Yuehua Li, Chuanfu Li, Li Liu, Zhengnian Ding |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2023-08-01
|
Series: | Translational Psychiatry |
Online Access: | https://doi.org/10.1038/s41398-023-02573-5 |
Similar Items
-
HSPA12A acts as a scaffolding protein to inhibit cardiac fibroblast activation and cardiac fibrosis
by: Qian Mao, et al.
Published: (2025-01-01) -
Environmental Control of Adult Neurogenesis: From Hippocampal Homeostasis to Behavior and Disease
by: Sjoukje D. Kuipers, et al.
Published: (2014-01-01) -
Exogenous lactate augments exercise-induced improvement in memory but not in hippocampal neurogenesis
by: Deunsol Hwang, et al.
Published: (2023-04-01) -
Dissecting the role of adult hippocampal neurogenesis towards resilience versus susceptibility to stress-related mood disorders
by: Katherine L. Jones, et al.
Published: (2022-07-01) -
Roles of microglia in adult hippocampal neurogenesis in depression and their therapeutics
by: Shaoyi Fang, et al.
Published: (2023-10-01)