Evaluation of RevX solution extract as a potential inhibitor of the main protease of SARS-CoV-2—In vitro study and molecular docking

Evaluation of RevX solution extract as a potential inhibitor of the main protease of SARS-CoV-2—In vitro study and molecular docking

The main protease (Mpro) of SARS-CoV-2 is a protease necessary for viral polyprotein processing and maturation. Mpro cleaves the polypeptide sequence after the glutamine residues. There is no known cellular protease with this substrate specificity in humans; therefore, it is considered an attractive...

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Bibliographic Details
Main Authors: Feng-Pai Chou, Chia-Chun Liu, Huynh Nguyet Huong Giang, Sheng-Cih Huang, Hsiu-Fu Hsu, Tung-Kung Wu
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Heliyon
Subjects:
Sorghum
Sterol
Mpro
GC-376
Antiviral drug
Online Access:http://www.sciencedirect.com/science/article/pii/S240584402200322X

Internet

http://www.sciencedirect.com/science/article/pii/S240584402200322X

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