Hyperfunction of CD4 CD25 regulatory T cells in de novo acute myeloid leukemia

Abstract Background Acute myeloid leukemia (AML) is a common hematopoietic malignancy that has a high relapse rate, and the number of regulatory T cells (Tregs) in AML patients is significantly increased. The aim of this study was to clarify the role of Tregs in the immune escape of acute myeloid le...

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Bibliographic Details
Main Authors: Yuling Wan, Congxiao Zhang, Yingxi Xu, Min Wang, Qing Rao, Haiyan Xing, Zheng Tian, Kejing Tang, Yingchang Mi, Ying Wang, Jianxiang Wang
Format: Article
Language:English
Published: BMC 2020-05-01
Series:BMC Cancer
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12885-020-06961-8