Protection Activity of 1,4-Naphthoquinones in Rotenone-Induced Models of Neurotoxicity

Protection Activity of 1,4-Naphthoquinones in Rotenone-Induced Models of Neurotoxicity

The MTS cell viability test was used to screen a mini library of natural and synthetic 1,4-naphthoquinone derivatives (1,4-NQs) from marine sources. This screening identified two highly effective compounds, <b>U-443</b> and <b>U-573</b>, which showed potential in protecting N...

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Bibliographic Details
Main Authors: Irina Agafonova, Ekaterina Chingizova, Elena Chaikina, Ekaterina Menchinskaya, Sergey Kozlovskiy, Galina Likhatskaya, Yuri Sabutski, Sergey Polonik, Dmitry Aminin, Evgeny Pislyagin
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Marine Drugs
Subjects:
1,4-naphthoquinones
neuronal cells
macrophages
rotenone
neuroprotection
Parkinson’s disease
Online Access:https://www.mdpi.com/1660-3397/22/2/62

Internet

https://www.mdpi.com/1660-3397/22/2/62

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