Protection Activity of 1,4-Naphthoquinones in Rotenone-Induced Models of Neurotoxicity

Protection Activity of 1,4-Naphthoquinones in Rotenone-Induced Models of Neurotoxicity

The MTS cell viability test was used to screen a mini library of natural and synthetic 1,4-naphthoquinone derivatives (1,4-NQs) from marine sources. This screening identified two highly effective compounds, <b>U-443</b> and <b>U-573</b>, which showed potential in protecting N...

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Bibliographic Details
Main Authors:	Irina Agafonova, Ekaterina Chingizova, Elena Chaikina, Ekaterina Menchinskaya, Sergey Kozlovskiy, Galina Likhatskaya, Yuri Sabutski, Sergey Polonik, Dmitry Aminin, Evgeny Pislyagin
Format:	Article
Language:	English
Published:	MDPI AG 2024-01-01
Series:	Marine Drugs
Subjects:	1,4-naphthoquinones neuronal cells macrophages rotenone neuroprotection Parkinson’s disease
Online Access:	https://www.mdpi.com/1660-3397/22/2/62

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