Oral administration of Lactobacillus brevis 23017 combined with ellagic acid attenuates intestinal inflammatory injury caused by Eimeria infection by activating the Nrf2/HO-1 antioxidant pathway

Oral administration of Lactobacillus brevis 23017 combined with ellagic acid attenuates intestinal inflammatory injury caused by Eimeria infection by activating the Nrf2/HO-1 antioxidant pathway

Abstract The aim of this study was to investigate whether oral administration of Lactobacillus brevis 23017 (LB) alone and in combination with ellagic acid inhibits ChTLR15/ChNLRP3/ChIL-1β by activating the Nrf2/HO-1 pathway to attenuate intestinal inflammatory injury. Two animal experiments were pe...

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Bibliographic Details
Main Authors: Xuelian Yang, Xinghui Pan, Zhipeng Jia, Bingrong Bai, Wenjing Zhi, Hang Chen, Chunli Ma, Dexing Ma
Format: Article
Language:English
Published: BMC 2022-03-01
Series:Veterinary Research
Subjects:
Lactobacillus brevis
ellagic acid
Nrf2/HO-1
ChTLR15/ChNLRP3
inflammatory injury
Online Access:https://doi.org/10.1186/s13567-022-01042-z

Internet

https://doi.org/10.1186/s13567-022-01042-z

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