Alternatively Splicing Interactomes Identify Novel Isoform-Specific Partners for NSD2

Nuclear receptor SET domain protein (NSD2) plays a fundamental role in the pathogenesis of Wolf–Hirschhorn Syndrome (WHS) and is overexpressed in multiple human myelomas, but its protein–protein interaction (PPI) patterns, particularly at the isoform/exon levels, are poorly understood. We explored t...

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Bibliographic Details
Main Authors: Weidi Wang, Yucan Chen, Jingjing Zhao, Liang Chen, Weichen Song, Li Li, Guan Ning Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.612019/full