Caffeine and Chlorogenic Acid Combination Attenuate Early-Stage Chemically Induced Colon Carcinogenesis in Mice: Involvement of oncomiR miR-21a-5p

Colorectal cancer (CRC) is one of most common cancers worldwide, with high rates of mortality. Epidemiological findings demonstrate that coffee consumption reduces the risk of developing CRC by ~13%. In general, in vivo and in vitro findings demonstrate the antiproliferative, antioxidant and proapop...

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Bibliographic Details
Main Authors: Ariane Rocha Bartolomeu, Guilherme Ribeiro Romualdo, Carmen Griñán Lisón, Zein Mersini Besharat, Juan Antonio Marchal Corrales, Maria Ángel García Chaves, Luís Fernando Barbisan
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/23/11/6292