Mathematical modeling of a real‐time isothermal amplification assay for Erwinia amylovora

A general mathematical model that describes the temporal behavior of a real‐time isothermal process used for nucleic acid amplification is derived. A monotonically‐increasing fluorescence signal s(t) generated and measured during the amplification reaction can be modeled in the form of a logistic fu...

Full description

Bibliographic Details
Main Authors: Michael I. Gordon, David P. Klemer, Skylar L. Fuller, Jeff H. Chang, Daniel R. Klemer, Melodie L. Putnam
Format: Article
Language:English
Published: Wiley 2019-10-01
Series:Engineering Reports
Subjects:
Online Access:https://doi.org/10.1002/eng2.12047