Probabilistic quotient’s work and pharmacokinetics’ contribution: countering size effect in metabolic time series measurements
Abstract Metabolomic time course analyses of biofluids are highly relevant for clinical diagnostics. However, many sampling methods suffer from unknown sample sizes, commonly known as size effects. This prevents absolute quantification of biomarkers. Recently, several mathematical post acquisition n...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-09-01
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Series: | BMC Bioinformatics |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12859-022-04918-1 |