Natural killer cells drive 4-1BBL positive uveal melanoma towards EMT and metastatic disease

Natural killer cells drive 4-1BBL positive uveal melanoma towards EMT and metastatic disease

Abstract Background Inflammation in the eye is often associated with aggravated ocular diseases such as uveal melanoma (UM). Poor prognosis of UM is generally associated with high potential of metastatic liver dissemination. A strong driver of metastatic dissemination is the activation of the epithe...

Full description

Bibliographic Details
Main Authors: Shi Yong Neo, Mariana M. S. Oliveira, Le Tong, Yi Chen, Ziqing Chen, Sonia Cismas, Nutsa Burduli, Anna Malmerfelt, Joey Kay Hui Teo, Kong-Peng Lam, Evren Alici, Leonard Girnita, Arnika K. Wagner, Lisa S. Westerberg, Andreas Lundqvist
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Natural killer cells
Uveal melanoma
Epithelial-to-mesenchymal transition
Online Access:https://doi.org/10.1186/s13046-023-02917-5

Internet

https://doi.org/10.1186/s13046-023-02917-5

Similar Items